For others, classification of a chemical shall be determined on the basis of the total weight of evidence using expert judgment. A.0.3 Classification Based on Weight of EvidenceĪ.0.3.1 For some hazard classes, classification results directly when the data satisfy the criteria. A chemical need not be classified when it can be shown by conclusive experimental data from scientifically validated test methods that the chemical is not biologically available.Ī.0.2.6 For classification purposes, epidemiological data and experience on the effects of chemicals on humans (e.g., occupational data, data from accident databases) shall be taken into account in the evaluation of human health hazards of a chemical. Test conditions need to be standardized so that the results are reproducible with a given substance, and the standardized test yields 'valid' data for defining the hazard class of concern.Ī.0.2.4 Existing test data are acceptable for classifying chemicals, although expert judgment also may be needed for classification purposes.Ī.0.2.5 The effect of a chemical on biological systems is influenced, by the physico-chemical properties of the substance and/or ingredients of the mixture and the way in which ingredient substances are biologically available. Any test that determines hazardous properties, which is conducted according to recognized scientific principles, can be used for purposes of a hazard determination for health hazards. A.0.2 Available Data, Test Methods and Test Data QualityĪ.0.2.1 There is no requirement for testing chemicals.Ī.0.2.2 The criteria for determining health hazards are test method neutral, i.e., they do not specify particular test methods, as long as the methods are scientifically validated.Ī.0.2.3 The term 'scientifically validated' refers to the process by which the reliability and the relevance of a procedure are established for a particular purpose. (c) Determination of whether the chemical will be classified as hazardous and the degree of hazard.Ī.0.1.2 For many hazard classes, the criteria are semi-quantitative or qualitative and expert judgment is required to interpret the data for classification purposes. (b) Subsequent review of those data to ascertain the hazards associated with the chemical (a) Identification of relevant data regarding the hazards of a chemical

Hazard classification incorporates three steps:

Appendix A to § 1910.1200 - Health Hazard Criteria (Mandatory) A.0 GENERAL CLASSIFICATION CONSIDERATIONS A.0.1 ClassificationĪ.0.1.1 The term 'hazard classification' is used to indicate that only the intrinsic hazardous properties of chemicals are considered.

Digit span test 2.3.1